TECHNOLOGY:  

New Brain Scans Reveal Tauopathy Underlying CTE and PTSD

AFFILIATION:   James J Peters VA Medical Center, Bronx, New York, United States

TECHNOLOGY SUMMARY

Track: Medical & Biotech
Area: Concussive Injuries
Tech Readiness: TRL 4

Tech Brief: CTE can underlie PTSD and is characterized by aggregation of brain protein tau detectable postmortem. New PET scans enable detection of tau during life. Our prototype is a footballer with PTSD symptoms (lability, irritability). Tau-PET highlighted the cortical grey-white-junction, a CTE-specific pattern. Tau-imaging enables diagnosis of CTE-/PTSD-pathology during life.

FIGURES OF MERIT

Value Proposition: This technology enables diagnosis of CTE tauopathy during life for the first time ever. This technology also promises to reveal the contribution of CTE to PTSD. Currently both CTE and PTSD are formulated as largely cognitive or psychological disorders. These scans provide evidence for structural pathology, enabling diagnosis and providing endpoints for clinical trials.

SHOWCASE SUMMARY

Org Type: Academic/Gov Lab
Booth Number: T821