Multifunctional Skin-adhesive Nanoparticles for UV Protection

AFFILIATION:   Yale University/StraDEFY, New Haven, Connecticut, United States


Track: Medical & Biotech
Area: Advanced Material Platforms
Tech Readiness: TRL 4

Tech Brief: Using our patented bioadhesive nanoparticle technology, we have created a longer-lasting, safer, and more effective sunscreen. Our pre-clinical data demonstrate improved efficacy, reduced cell toxicity, and increased retention time on the skin. Moreover, this platform accommodates a variety of agents, including antibiotics, antifungals, DEET/insect repellents, and therapeutics.


Value Proposition: According to the World Congress on Cancers of the Skin, deployed military personnel are not being adequately protected from the most prevalent type of cancer. Seventy-seven percent of soldiers report being exposed to bright sunlight for more than four hours per day, while a staggering 62% report getting sunburnt, many to the point of blistering skin. Unsurprisingly, the vast majority, nearly 73%, report have limited or no access to sunscreen. In the past decade, operations have moved toward equatorial latitudes, such as Iraq and Afghanistan, increasing the sun exposure levels of service personnel. Without adequate protection, this UV exposure poses significant risk for the development of skin cancer--melanoma prevalence for veterans is six times greater than for civilian populations. Our long-lasting, bioadhesive sunscreen would provide durable protection for defense personnel without the need for reapplication, drastically reducing their skin cancer risk. Moreover, the tunable properties of this technology allow for controlled drug release, making it the ideal vehicle for localized, topical chemotherapeutic skin cancer treatment for afflicted veterans. We also have proof-of-concept data that this versatile platform can also deliver antibiotics, antifungals, insect repellents, and wound healing agents, as desired by national agencies.


Org Type: Early-stage Startup (Seed)